45,013 research outputs found

    The status of environmental satellites and availability of their data products

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    The latest available information about the status of unclassified environmental satellite (flown by the United States) and their data products is presented. The type of environmental satellites discussed include unmanned earth resource and meteorological satellites, and manned satellites which can act as a combination platform for instruments. The capabilities and data products of projected satellites are discussed along with those of currently operating systems

    Kelvin-Helmholtz Instability in a Weakly Ionized Medium

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    Ambient interstellar material may become entrained in outflows from massive stars as a result of shear flow instabilities. We study the linear theory of the Kelvin - Helmholtz instability, the simplest example of shear flow instability, in a partially ionized medium. We model the interaction as a two fluid system (charged and neutral) in a planar geometry. Our principal result is that for much of the relevant parameter space, neutrals and ions are sufficiently decoupled that the neutrals are unstable while the ions are held in place by the magnetic field. Thus, we predict that there should be a detectably narrower line profile in ionized species tracing the outflow compared with neutral species since ionized species are not participating in the turbulent interface with the ambient ISM. Since the magnetic field is frozen to the plasma, it is not tangled by the turbulence in the boundary layer.Comment: 21 pages, 4 figure

    A pilot study of the S-MAP (Solutions for Medications Adherence Problems) intervention for older adults prescribed polypharmacy in primary care: Study protocol

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    Background: Adhering to multiple medications as prescribed is challenging for older patients (aged ≥ 65 years) and a difficult behaviour to improve. Previous interventions designed to address this have been largely complex in nature but have shown limited effectiveness and have rarely used theory in their design. It has been recognised that theory ('a systematic way of understanding events or situations') can guide intervention development and help researchers better understand how complex adherence interventions work. This pilot study aims to test a novel community pharmacy-based intervention that has been systematically developed using the Theoretical Domains Framework (12-domain version) of behaviour change. Methods: As part of a non-randomised pilot study, pharmacists in 12 community pharmacies across Northern Ireland (n = 6) and London, England (n = 6), will be trained to deliver the intervention to older patients who are prescribed ≥ 4 regular medicines and are non-adherent (self-reported). Ten patients will be recruited per pharmacy (n = 120) and offered up to four tailored one-to-one sessions, in the pharmacy or via telephone depending on their adherence, over a 3-4-month period. Guided by an electronic application (app) on iPads, the intervention content will be tailored to each patient's underlying reasons for non-adherence and mapped to the most appropriate solutions using established behaviour change techniques. This study will assess the feasibility of collecting data on the primary outcome of medication adherence (self-report and dispensing data) and secondary outcomes (health-related quality of life and unplanned hospitalisations). An embedded process evaluation will assess training fidelity for pharmacy staff, intervention fidelity, acceptability to patients and pharmacists and the intervention's mechanism of action. Process evaluation data will include audio-recordings of training workshops, intervention sessions, feedback interviews and patient surveys. Analysis will be largely descriptive. Discussion: Using pre-defined progression criteria, the findings from this pilot study will guide the decision whether to proceed to a cluster randomised controlled trial to test the effectiveness of the S-MAP intervention in comparison to usual care in community pharmacies. The study will also explore how the intervention components may work to bring about change in older patients' adherence behaviour and guide further refinement of the intervention and study procedures. Trial registration: This study is registered at ISRCTN: https://doi.org/10.1186/ISRCTN7383153

    Resonantly enhanced and diminished strong-field gravitational-wave fluxes

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    The inspiral of a stellar mass (1100M1 - 100\,M_\odot) compact body into a massive (105107M10^5 - 10^7\,M_\odot) black hole has been a focus of much effort, both for the promise of such systems as astrophysical sources of gravitational waves, and because they are a clean limit of the general relativistic two-body problem. Our understanding of this problem has advanced significantly in recent years, with much progress in modeling the "self force" arising from the small body's interaction with its own spacetime deformation. Recent work has shown that this self interaction is especially interesting when the frequencies associated with the orbit's θ\theta and rr motions are in an integer ratio: Ωθ/Ωr=βθ/βr\Omega_\theta/\Omega_r = \beta_\theta/\beta_r, with βθ\beta_\theta and βr\beta_r both integers. In this paper, we show that key aspects of the self interaction for such "resonant" orbits can be understood with a relatively simple Teukolsky-equation-based calculation of gravitational-wave fluxes. We show that fluxes from resonant orbits depend on the relative phase of radial and angular motions. The purpose of this paper is to illustrate in simple terms how this phase dependence arises using tools that are good for strong-field orbits, and to present a first study of how strongly the fluxes vary as a function of this phase and other orbital parameters. Future work will use the full dissipative self force to examine resonant and near resonant strong-field effects in greater depth, which will be needed to characterize how a binary evolves through orbital resonances.Comment: 25 pages, 6 figures, 4 tables. Accepted to Phys Rev D; accepted version posted here, including referee feedback and other useful comment

    Development of primary invasive pneumococcal disease caused by serotype 1 pneumococci is driven by early increased type I interferon response in the lung

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    The pneumococcus is the world's foremost respiratory pathogen, but the mechanisms allowing this pathogen to proceed from initial asymptomatic colonization to invasive disease are poorly understood. We have examined the early stages of invasive pneumococcal disease (IPD) by comparing host transcriptional responses to an invasive strain and a noninvasive strain of serotype 1 Streptococcus pneumoniae in the mouse lung. While the two strains were present in equal numbers in the lung 6 h after intranasal challenge, only the invasive strain (strain 1861) had invaded the pleural cavity at that time point; this correlated with subsequent development of bacteremia in mice challenged with strain 1861 but not the noninvasive strain (strain 1). Progression beyond the lung was associated with stronger induction of the type I interferon (IFN-I) response in the lung at 6 h. Suppression of the IFN-I response through administration of neutralizing antibody to IFNAR1 (the receptor for type I interferons) led to significantly reduced invasion of the pleural cavity by strain 1861 at 6 h postchallenge. Our data suggest that strong induction of the IFN-I response is a key factor in early progression of invasive serotype 1 strain 1861 beyond the lung during development of IPD

    Journey Beyond the Fair

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    Journey Beyond the Fair will combine a vast virtual world environment and hand-held devices to develop a tightly coupled home-school-museum paradigm that enhances traditional exhibits. This paradigm is designed to work as a national model where informal humanities education institutions can add depth of learning and heighten the level of interactivity and personalization of an onsite experience by strengthening the connections to a home/school-based virtual world experience. While in this instance we are addressing the 1964/65 New York World's Fair, institutions can adapt the concept based on subjects pertinent to their facility, culture and demographic visitation needs

    Exploring the Physics of Type Ia Supernovae Through the X-ray Spectra of their Remnants

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    We present the results of an ongoing project to use the X-ray observations of Type Ia Supernova Remnants to constrain the physical processes involved in Type Ia Supernova explosions. We use the Tycho Supernova Remnant (SN 1572) as a benchmark case, comparing its observed spectrum with models for the X-ray emission from the shocked ejecta generated from different kinds of Type Ia explosions. Both the integrated spectrum of Tycho and the spatial distribution of the Fe and Si emission in the remnant are well reproduced by delayed detonation models with stratified ejecta. All the other Type Ia explosion models fail, including well-mixed deflagrations calculated in three dimensions.Comment: 5 pages, 3 figures, to appear in the proceedings of the "Stellar end products" workshop, 13-15 April 2005, Granada, Spain, ed. M.A. Perez-Torres, Vol. 77 (Jan 2006) of MmSA

    Plane-wave impulse approximation extraction of the neutron magnetic form factor from quasielastic ^3He(e,e') at Q^2=0.3 to 0.6 (GeV/c)^2

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    A high precision measurement of the transverse spin-dependent asymmetry A_T' in ^3He(e,e') quasielastic scattering was performed in Hall A at Jefferson Lab at values of the squared four-momentum transfer, Q^2, between 0.1 and 0.6 (GeV/c)^2. A_(T') is sensitive to the neutron magnetic form factor, G_M^n . Values of G_M^n at Q^2 = 0.1 and 0.2 (GeV/c)^2, extracted using Faddeev calculations, were reported previously. Here, we report the extraction of G_M^n for the remaining Q^2 values in the range from 0.3 to 0.6 (GeV/c)^2 using a plane-wave impulse approximation calculation. The results are in good agreement with recent precision data from experiments using a deuterium target

    Analytical modeling of circuit aerodynamics in the new NASA Lewis wind tunnel

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    Rehabilitation and extention of the capability of the altitude wind tunnel (AWT) was analyzed. The analytical modeling program involves the use of advanced axisymmetric and three dimensional viscous analyses to compute the flow through the various AWT components. Results for the analytical modeling of the high speed leg aerodynamics are presented; these include: an evaluation of the flow quality at the entrance to the test section, an investigation of the effects of test section bleed for different model blockages, and an examination of three dimensional effects in the diffuser due to reentry flow and due to the change in cross sectional shape of the exhaust scoop
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